Faculty & Adjunct Professors (BSE): Nopphon Weeranoppanant


Topic Expertise:


Novel engineering for chemical and biochemical processes


Contact:


School of Biomolecular Science & Engineering (BSE), 

Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong, THAILAND

Tel: (+66)33 014 020 | Email: nopphon_w@vistec.ac.th






Dr. Nopphon Weeranoppanant pursued his B.S. (2011) in Chemical Engineering at Columbia University, New York, USA. He then moved to Massachusetts Institute of Technology (MIT) to obtain a M.S.CEP. (2013) during which he also had opportunities to be technical consultants at General Mills (Minessota, USA) and  Merck Sharp & Dohme Corp. (Singapore). He then received a Ph.D. in Chemical Engineering at MIT, USA. Prior to taking an academic position in Thailand, he was a director of research for Zaiput flow technologies, a MIT-spinoff startup focusing on novel flow-chemistry devices. He currently holds a dual faculty position at Burapha University and School of Biomolecular Science and Engineering, VISTEC.


Dr. Nopphon received numerous awards and fellowships including Charles F. Bonilla Medal (Columbia University, 2011), David H. Koch Fellowship (MIT, 2011), Postdoctoral fellowship at Novartis-MIT Center for Continuous Manufacturing (MIT, 2016), Delegate of Thailand to the 67th Lindau Nobel Laureate Meetings (2017), Excellent thesis award from National Research Council of Thailand (2018), and Emerging Investigator (Reaction Chemistry & Engineering journal (2019).




Research overview:


Novel engineering of chemical and biochemical processes

Our multidisciplinary research group focuses on engineering aspects of chemical and biochemical processes. The work in our group can be mainly categorized into three main parts. In the first part, we are interested in developing a continuous-flow process for challenging chemical and biochemical reactions. Flow chemistry is a promising alternative to batch chemistry as it is safe and efficient. Our previous work includes the development of multistep flow synthesis of active pharmaceutical ingredients as well as the continuous homogeneous catalyzed oxidation. In the second part, we aim to design novel separation and purification techniques. This part often involves studies of multiphase systems (liquid/liquid, gas/liquid). In addition, our research group is also interested in optimization of conventional separation techniques for chemical and biochemical processes such as membrane technology, evaporation, and distillation. In the last part, we aim to study process integration from upstream (synthesis or fermentation) to downstream (recovery, purification). We apply theoretical studies as well as simulation with different experimental strategies to obtain a process that is technically and economically feasible.




Publication output:


Journal, Article

Application of Box-Behnken design in monoglycerides production via glycerolysis of palm oil using homogenizer reactor

Hiranlordsanti P.

Industrial Crops and Products ,2024, 222 119631




Journal, Article

Continuous Flow Hydroxylation of Benzene to Phenol in a Photocatalytic Millistructured Flat-Plate Reactor

Khositanon C.

ACS Sustainable Chemistry and Engineering ,2024, 1237 




Journal, Article

Self-shuttle-mediated electron transfer to boost photocatalytic hydrogen production of Co-Zn bimetallic MOF

Saothayanun T.K.

Journal of Materials Chemistry A ,2024, 1239 




Journal, Article

Integrated Continuous-Flow Production of Wax Esters Combining Whole-Cell and In Vitro Biocatalysis

Buttranon S.

Organic Process Research and Development ,2024, 285 




Journal, Article

Continuous-flow chemo-enzymatic gram-scale synthesis of indole-3-acetic acid

Mapinta S.

Green Chemistry ,2024, undefined 




Journal, Article

Optimization of Lipid-Based Nanoparticles Formulation Loaded with Biological Product Using A Novel Design Vortex Tube Reactor via Flow Chemistry

Suwanpitak K.

International Journal of Nanomedicine ,2024, 19 




Journal, Review

Continuous flow synthesis: A promising platform for the future of nanoparticle-based drug delivery

Huanbutta K.

Journal of Drug Delivery Science and Technology ,2024, 91 105265




Journal, Article

Modeling of continuous hydrogen fermentation integrated with continuous in-line liquid-liquid extraction

Chaichol P.

Bioresource Technology Reports ,2023, 24 101651




Journal, Article

Efficient Enzymatic Cascade Synthesis of α-Olefins via Colocalization onto Graphene Oxides and Liquid-Liquid Extraction

Worrarat N.

Industrial and Engineering Chemistry Research ,2023, 6247 




Journal, Article

Continuous monooxygenase-mediated biodegradation of phenol derivatives in wastewater: Optimization of flow conditions

Naramittanakul A.

Journal of Environmental Chemical Engineering ,2023, 115 111010




Journal, Article

Metal additives for boosting hydrogen production in anaerobic fermentation: Focus on the change of gene expression and cost analysis

Tirapanampai C.

Journal of Cleaner Production ,2023, 414 137609




Journal, Review

Advances in in situ and in-line liquid-liquid extraction for bioprocess intensification

Chaichol P.

Reaction Chemistry and Engineering ,2023, 810 




Journal, Article

Pyrene as a Triplet Acceptor Enhancing Triplet Energy Transfer of g-C3N4 in Heterogeneous Photooxidation

Li L.

Journal of Physical Chemistry C ,2023, 12726 




Journal, Article

Anaerobic co-digestion of yard waste, food waste, and pig slurry in a batch experiment: An investigation on methane potential, performance, and microbial community

Pongsopon M.

Bioresource Technology Reports ,2023, 21 101364




Journal, Article

Continuous Fatty Acid Production: Comparative Technoeconomic and Life-Cycle Analysis between Subcritical Water and Lipase Methods

Thakhiew P.

ACS Sustainable Chemistry and Engineering ,2022, 1045 




Journal, Article

Solid-Liquid separation through sieve mesh for enhancing biogas production in a swine farm

Woraruthai T.

International Journal of Energy Research ,2022, 4611 




Journal, Article

Processing of palm oil mill effluent (POME) into food waste digesting microbes: An investigation of acclimatization strategies

Tirapanampai C.

Sustainable Energy Technologies and Assessments ,2022, 52 102287




Journal, Article

Reconfiguring workup steps in multi-cycle extractive bioconversion for sustainable fatty alcohol production: A process engineering approach

Buttranon S.

Reaction Chemistry and Engineering ,2022, 72 




Journal, Article

Simple Fabrication of a Continuous-Flow Photocatalytic Reactor Using Dopamine-Assisted Immobilization onto a Fluoropolymer Tubing

Khositanon C.

Industrial and Engineering Chemistry Research ,2022, 613 




Book, Book Chapter

Flow Technologies for Efficient Separations

Weeranoppanant N.

Sustainable Separation Engineering: Materials, Techniques and Process Development ,2022, undefined 




Book, Book Chapter

Continuous gas-liquid and liquid-liquid separation

Weeranoppanant N.

Flow Chemistry - Fundamentals: Second Edition ,2021, 1 




Journal, Review

Development of a continuous-flow system with immobilized biocatalysts towards sustainable bioprocessing

Naramittanakul A.

Reaction Chemistry and Engineering ,2021, 610 




Journal, Review

Enzymes, in Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability

Intasian P.

Chemical Reviews ,2021, 12117 




Journal, Article

Antibiotics armed neutrophils as a potential therapy for brain fungal infection caused by chemotherapy-induced neutropenia

Han Y.

Biomaterials ,2021, 274 120849




Journal, Review

Bioengineering of nano metal-organic frameworks for cancer immunotherapy

Chong G.

Nano Research ,2021, 145 




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