Topic Expertise:
Novel engineering for chemical and biochemical processes
Contact:
School of Biomolecular Science & Engineering (BSE),
Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong, THAILAND
Tel: (+66)33 014 020 | Email: nopphon_w@vistec.ac.th
Dr. Nopphon Weeranoppanant pursued his B.S. (2011) in Chemical Engineering at Columbia University, New York, USA. He then moved to Massachusetts Institute of Technology (MIT) to obtain a M.S.CEP. (2013) during which he also had opportunities to be technical consultants at General Mills (Minessota, USA) and Merck Sharp & Dohme Corp. (Singapore). He then received a Ph.D. in Chemical Engineering at MIT, USA. Prior to taking an academic position in Thailand, he was a director of research for Zaiput flow technologies, a MIT-spinoff startup focusing on novel flow-chemistry devices. He currently holds a dual faculty position at Burapha University and School of Biomolecular Science and Engineering, VISTEC.
Dr. Nopphon received numerous awards and fellowships including Charles F. Bonilla Medal (Columbia University, 2011), David H. Koch Fellowship (MIT, 2011), Postdoctoral fellowship at Novartis-MIT Center for Continuous Manufacturing (MIT, 2016), Delegate of Thailand to the 67th Lindau Nobel Laureate Meetings (2017), Excellent thesis award from National Research Council of Thailand (2018), and Emerging Investigator (Reaction Chemistry & Engineering journal (2019).
Research overview:
Novel engineering of chemical and biochemical processes
Our multidisciplinary research group focuses on engineering aspects of chemical and biochemical processes. The work in our group can be mainly categorized into three main parts. In the first part, we are interested in developing a continuous-flow process for challenging chemical and biochemical reactions. Flow chemistry is a promising alternative to batch chemistry as it is safe and efficient. Our previous work includes the development of multistep flow synthesis of active pharmaceutical ingredients as well as the continuous homogeneous catalyzed oxidation. In the second part, we aim to design novel separation and purification techniques. This part often involves studies of multiphase systems (liquid/liquid, gas/liquid). In addition, our research group is also interested in optimization of conventional separation techniques for chemical and biochemical processes such as membrane technology, evaporation, and distillation. In the last part, we aim to study process integration from upstream (synthesis or fermentation) to downstream (recovery, purification). We apply theoretical studies as well as simulation with different experimental strategies to obtain a process that is technically and economically feasible.
Publication output:
Journal, Article
Application of Box-Behnken design in monoglycerides production via glycerolysis of palm oil using homogenizer reactor
Hiranlordsanti P.
Industrial Crops and Products ,2024, 222 119631
Journal, Article
Continuous Flow Hydroxylation of Benzene to Phenol in a Photocatalytic Millistructured Flat-Plate Reactor
Khositanon C.
ACS Sustainable Chemistry and Engineering ,2024, 1237
Journal, Article
Self-shuttle-mediated electron transfer to boost photocatalytic hydrogen production of Co-Zn bimetallic MOF
Saothayanun T.K.
Journal of Materials Chemistry A ,2024, 1239
Journal, Article
Integrated Continuous-Flow Production of Wax Esters Combining Whole-Cell and In Vitro Biocatalysis
Buttranon S.
Organic Process Research and Development ,2024, 285
Journal, Article
Continuous-flow chemo-enzymatic gram-scale synthesis of indole-3-acetic acid
Mapinta S.
Green Chemistry ,2024, undefined
Journal, Article
Optimization of Lipid-Based Nanoparticles Formulation Loaded with Biological Product Using A Novel Design Vortex Tube Reactor via Flow Chemistry
Suwanpitak K.
International Journal of Nanomedicine ,2024, 19
Journal, Review
Continuous flow synthesis: A promising platform for the future of nanoparticle-based drug delivery
Huanbutta K.
Journal of Drug Delivery Science and Technology ,2024, 91 105265
Journal, Article
Modeling of continuous hydrogen fermentation integrated with continuous in-line liquid-liquid extraction
Chaichol P.
Bioresource Technology Reports ,2023, 24 101651
Journal, Article
Efficient Enzymatic Cascade Synthesis of α-Olefins via Colocalization onto Graphene Oxides and Liquid-Liquid Extraction
Worrarat N.
Industrial and Engineering Chemistry Research ,2023, 6247
Journal, Article
Continuous monooxygenase-mediated biodegradation of phenol derivatives in wastewater: Optimization of flow conditions
Naramittanakul A.
Journal of Environmental Chemical Engineering ,2023, 115 111010
Journal, Article
Metal additives for boosting hydrogen production in anaerobic fermentation: Focus on the change of gene expression and cost analysis
Tirapanampai C.
Journal of Cleaner Production ,2023, 414 137609
Journal, Review
Advances in in situ and in-line liquid-liquid extraction for bioprocess intensification
Chaichol P.
Reaction Chemistry and Engineering ,2023, 810
Journal, Article
Pyrene as a Triplet Acceptor Enhancing Triplet Energy Transfer of g-C3N4 in Heterogeneous Photooxidation
Li L.
Journal of Physical Chemistry C ,2023, 12726
Journal, Article
Anaerobic co-digestion of yard waste, food waste, and pig slurry in a batch experiment: An investigation on methane potential, performance, and microbial community
Pongsopon M.
Bioresource Technology Reports ,2023, 21 101364
Journal, Article
Continuous Fatty Acid Production: Comparative Technoeconomic and Life-Cycle Analysis between Subcritical Water and Lipase Methods
Thakhiew P.
ACS Sustainable Chemistry and Engineering ,2022, 1045
Journal, Article
Solid-Liquid separation through sieve mesh for enhancing biogas production in a swine farm
Woraruthai T.
International Journal of Energy Research ,2022, 4611
Journal, Article
Processing of palm oil mill effluent (POME) into food waste digesting microbes: An investigation of acclimatization strategies
Tirapanampai C.
Sustainable Energy Technologies and Assessments ,2022, 52 102287
Journal, Article
Reconfiguring workup steps in multi-cycle extractive bioconversion for sustainable fatty alcohol production: A process engineering approach
Buttranon S.
Reaction Chemistry and Engineering ,2022, 72
Journal, Article
Simple Fabrication of a Continuous-Flow Photocatalytic Reactor Using Dopamine-Assisted Immobilization onto a Fluoropolymer Tubing
Khositanon C.
Industrial and Engineering Chemistry Research ,2022, 613
Book, Book Chapter
Flow Technologies for Efficient Separations
Weeranoppanant N.
Sustainable Separation Engineering: Materials, Techniques and Process Development ,2022, undefined
Book, Book Chapter
Continuous gas-liquid and liquid-liquid separation
Weeranoppanant N.
Flow Chemistry - Fundamentals: Second Edition ,2021, 1
Journal, Review
Development of a continuous-flow system with immobilized biocatalysts towards sustainable bioprocessing
Naramittanakul A.
Reaction Chemistry and Engineering ,2021, 610
Journal, Review
Enzymes, in Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability
Intasian P.
Chemical Reviews ,2021, 12117
Journal, Article
Antibiotics armed neutrophils as a potential therapy for brain fungal infection caused by chemotherapy-induced neutropenia
Han Y.
Biomaterials ,2021, 274 120849
Journal, Review
Bioengineering of nano metal-organic frameworks for cancer immunotherapy
Chong G.
Nano Research ,2021, 145